1. Pharmacological treatment (the most common)
Levodopa + Carbidopa/BenserazidaIt is the most effective treatment for stiffness, slowness and tremors.
It adjusts over time.
Dopaminergic agonists(Pramipexol, ropinirol, rotigotina)
They act as dopamine imitators.
They are used at the start or in combination with levodopa.
MAO-B inhibitors(Rasagilina, selegilina, safinamida)
They help make dopamine last longer in the brain.
COMT Inhibitors(Entacapona, opicapona)
They are added when the levodope starts to “cut” earlier.
AmantadinaUseful for dyskinesia ( involuntary movements).
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2. Non-pharmacological treatments (equal important) Kinesiology / PhysiotherapyImprove your gait, balance and strength.
Reduce the risk of falls.
FonoaudiologíaFor low voice (hypophonia), difficulty swallowing or speaking.
Occupational therapyTo adapt at home and in everyday activities.
Regular physical activityThe best complementary treatment.
Boxing, fast walking, cycling, pilates, dance, strength exercises.
Psychology / emotional supportFor anxiety, fear, depression or diagnosis adjustment.
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3. Surgery – Deep Brain Stimulation (DBS)For people with several years of evolution and severe fluctuations.
Implants electrodes that regulate areas of the brain.
Reduces tremors, stiffness and dyskinesia.
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4. Life styleMediterranean diet (rich in fruits, vegetables, fish, olive oil).
Dormir bien.
Keep in touch and social activities.
Avoid intense stress (and worse symptoms).
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5. Periodic neurological check upMedication adjustments, gait assessment, emotional state, sleep, and nutrition.
