A Japanese research team announced it will start human clinical trials for a new Parkinson’s disease treatment.
On Monday, a team from Kyoto University’s Center for iPS Cell Research and Application announced it will begin testing the new treatment on humans after successful rounds of animal trials. The injected treatment uses stem cells to help those with Parkinson’s diseases and received approval from the government.
Parkinson’s disease affects about 10 million around the world, including 1 million in the United States, according to the Parkinson’s Foundation. Parkinson’s disease reduces neurons in the brain that produce dopamine. This loss of cells causes tremors in the feet and hands. It also causes stiffness in someone’s body. Treatments exist for those symptoms, but scientists haven’t been able to find a cure. This treatment could be a breakthrough option for those with Parkinson’s disease.
The team plans to inject induced Pluripotent Stem (iPS) cells into the patient’s brains. The 5 million injected cells have the potential to develop into any cell in the body—including the neurons that produce dopamine. The iPS cell technology was created at Kyoto University in 2006 and can be generated from adult cells, which means the treatment doesn’t require the use of embryonic stem cells. The creator of the technology, Shinya Yamanaka, was awarded a Nobel Prize in 2012 for the finding.
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